Résumé:
Depression is a complex and debilitating mental health disorder that affects
millions worldwide. This dissertation investigates the multifaceted nature of
depression through a comprehensive literature review, an in-depth analysis of
Brain-Derived Neurotrophic Factor (BDNF), and a statistical study of
demographic factors and treatment patterns. The literature review elucidates
various aspects of depression, from clinical presentation to epidemiological
insights and current treatment options, highlighting ongoing management
challenges. Additionally, it examines the role of (BDNF) in the
pathophysiology of depression, confirming its intricate link to depressive
states and reinforcing its potential as a biomarker for diagnosis and
therapeutic targeting. It also presents a statistical study revealing no
significant associations between demographic factors and prescribed
therapeutic classes for depression, suggesting the need for tailored
therapeutic strategies that consider individual patient profiles. The findings
highlight the critical importance of further research, and the subjectivity of
currently used methods in the the diagnosis and prescription of
antidepressants, which reinforces the importance of integrating biomarkers
such as BDNF and adopting more personalized and effective approaches to
managing depression
